Effortless 3D Cell Culture: Save Time, Reduce Costs, and Achieve Reliable Results

CERO 3D Incubator and Bioreactor - optimized cultivation of stem cells, spheroids, organoids and tissue biopsies

Trusted by hundreds of labs worldwide

Saving time, enhancing quality, and paving new paths.

Prof. Dr. L. Sevenich and Anna Wolfram

Scalable stem cell processes with minimal starting volumes.

Dr. J. Neubauer | Managing Director at Fraunhofer Project Center for Stem Cell Process Technology

CERO 3D advances liver tissue research like never before.

Prof. Dr. A. Nüssler and Prof. Dr. S. Ehnert

Your Challenges in 3D Cell Culture

The differentiation of pluripotent stem cells often result in a heterogeneous cell population.

Organoids lose their structure and metabolic activity during long-term culture.

Time-consuming manual maintenance like media changes.

High costs for consumables and substrates.

Solved by CERO 3D Incubator and Bioreactor

Level-Up Your Research with Cutting-Edge 3D Cell Culture

Enhanced Cell Viability and Vitality

The CERO 3D’s low-shear bi-directional rotation reduces cell stress and ensures optimal nutrigen supply, supporting enhanced cell survival, maturation, and differentiation. This design minimizes damage to delicate cell structures, allowing for long-term cultures without compromising cell health.

Flexible & Scalable

Suitable for a wide range of cell types—including stem cells, tumor cells, and even tissue biopsies—CERO 3D delivers high-quality 3D culture capabilities to labs of all sizes. With four disposable, individually controlled tubes, CERO 3D make it easy to scale up, replacing a full incubator while using only minimal space on the benchtop.

Automated Environmental Control

The system offers precise control over essential culture prarmeters such as CO₂, temperature, and pH. This ensures optimal conditions for the differentiation, maturation, and growth of various cell types and 3D-structures including organoids and tissue biopsies.

Budget-friendly & Easy handling

Experience intuitive operation with minimal hands-on time. Special culture vessels enable 4-minute media changes, reduce media usage, and eliminate the need for embedding substrates. This ensures time- and cost-efficient cultivation of high-quality 3D structures.

Extended Culturing for Long-Term Studies

Built for durability, the CERO 3D supports cultures from days to months, making it ideal for long-term studies such as regenerative medicine, cancer research, and viral infections, as well as the complete maturation of cells.

Advanced 3D Cell Culture

Experience realistic cell growth with 3D cell culture that promotes more realistic cell behavior and interactions compared to traditional 2D cultures, offering improved accuracy for applications in cancer research, tissue modeling, and regenerative medicine.

Increased cell vitality and homogeneity of cell populations.

Reduces costs by optimizing consumable usage.

Simplified handling and reduced manual workload.

Reproducibility and reability you can trust.

Applications

„With CERO 3D, we increased the size of our organoids by 50% while cutting manual labor in half. Our research is now more precise and efficient.“

– Dr. Anna Miller, Head of Cancer Research

Publications

See the publications reference